![]() ![]() ![]() Green Goblin | Tombstone | Doctor Octopus | Hammerhead | Venom ( Eddie Brock) | Sinister Six ( Rhino, Vulture, Electro, Sandman, Mysterio, and Kraven the Hunter) | Chameleon | Tinkerer | Enforcers ( Shocker, Ricochet and Ox) | Molten Man | Silver Sable | Harry Osborn | Lizard | J. Harry Osborn | Electro | Kraven the Hunter | Turbo Jet | Kingpin | Lizard | Shikata | Silver Sable Kingpin | Green Goblin ( Norman Osborn and Harry Osborn) | Doctor Octopus | Hobgoblin | Venom | Vanessa Fisk | Richard Fisk | Insidious Six ( Scorpion, Rhino, Mysterio, Chameleon, Shocker, and Vulture) | Black Cat | Lizard | Morbius | Spider-Carnage | Spider-Slayers ( Alistair Smythe) | Carnage | Baron Mordo | Dormammu | Silver Sable | Hydro-Man | Prowler | Doctor Doom | Red Skull | Electro | Hammerhead | Tombstone | Punisher | Kraven the Hunter | Calypso | Herbert Landon | Jackal | Owl | Spot | Beyonder | J. Green Goblin | Kraven the Hunter | Doctor Doom | Swarm | Chameleon | Electro | Brotherhood of Mutants ( Magneto, Blob, Toad, and Mastermind) | Mysterio | Loki Laufeyson | Ymir | Mordred | Kingpin | Doctor Faustus | Red Skull | Juggernaut | Shocker | Sandman | Dracula | Scorpion | Beetle | Doctor Octopus | A.I.M. Jonah JamesonÄoctor Doom | Kingpin | Doctor Octopus | Lizard | Black Cat | Sandman | Magneto | Mysterio | Ringmaster | Green Goblin | Sidewinder | Kraven the Hunter | Red Skull | Chameleon | Vulture | Hammerhead | Wizard Matto Magneto | Enforcers ( Cowboy and Ox) | Frederick Foswell | Mole Man | J. Vulture | Green Goblin | Electro | Rhino | Mysterio | Doctor Octopus | Scorpion | Human Fly | Kingpin | Lizard | Spider-Slayer | Sandman | Dr. Spider-Man: Far From Home: Mysterio's Crew ( Mysterio, William Ginter Riva, Victoria Snow, Gutes Guterman, Janice Lincoln, & Doug) | Elementals ( Molten Man, Hydro-Man, Sandman, Cyclone and Elemental Fusion) | Skrulls ( Talos) | Obadiah Stane | J. Spider-Man: Into the Spider-Verse: Kingpin | Doctor Octopus | Prowler | Tombstone | Scorpion | Green Goblin | Vanessa Fisk | Richard Fisk Spider-Man: Homecoming: Bestman Salvage ( Vulture, Tinkerer, Shocker #1, Shocker #2 & Randy Vale) | Mac Gargan | Aaron Davis The Amazing Spider-Man 2: Electro | Green Goblin | Donald Menken | Rhino | Alistair Smythe | Ashley Kafka | Felicia Hardy | Gustav Fiers | Norman Osborn The Amazing Spider-Man: Lizard | Gustav Fiers | Cash Register Thief | Norman Osborn Jonah Jameson | Green Goblin | Dennis Carradine Spider-Man 3: Venom | Sandman | New Goblin | J. Spider-Man 2: Doctor Octopus | Harry Osborn | J. Spider-Man: Green Goblin | Dennis Carradine | Bank Robbers | Harry Osborn | J. Mysterio ( Quentin Beck, Daniel Berkhart and Francis Klum) | Green Goblin ( Norman Osborn, Harry Osborn and Bart Hamilton) | He ultimately defeats the duo, leaving only Mister Negative and Doctor Octopus left. After having to fight against the hallucinations of his own mind and barely escaping, Spider-Man has a second encounter with Scorpion, who is now accompanied by Rhino. He then has an encounter with Scorpion, who poisons him. Meanwhile, Vulture teams up with Electro and together they set up a trap for Spider-Man, although he manages to defeat them. Thus, they form the Sinister Six, with the singular goal of destroying Norman Osborn and Oscorp. He had researched all of the most violent, offering each of them something unique if they were to help him. Otto assumes the mantle of Doctor Octopus to exact his revenge, breaking criminals out of Ryker's Prison and The Raft. Past history showed that, while they had worked together as scientists and co-founded Oscorp, Norman was quick to break the rules, such as when he used an untested substance on a young Martin Li and inadvertently created Mister Negative. Norman had already removed funding from his projects at this point and, according to Otto, stolen his ideas and technology. After Mayor Osborn claims credit for the capture of Mister Negative, this infuriates Otto Octavius and pushes him over the edge. ![]()
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